STUDIES ON SECRETORY ACTIVITY OF PEPSINOGEN
نویسندگان
چکیده
منابع مشابه
Studies on the dynamics of pepsinogen distribution.
Distribution of materials (such as enzymes) between the alimentary canal and the blood stream is a complex process involving the factors of synthesis, movement into one or more compartments, and destruction.' An initial attempt to quantitate these events is presented. A theory and methodology are developed and illustrated by preliminary data on the distribution of pepsinogen. The general approa...
متن کاملImmunological Studies on Pepsin and Pepsinogen
1. Alkali (pH 7.6)-denatured pepsins from swine, cattle, and guinea pigs precipitate in swine pepsin antiserum. Similarly treated pepsins from the rabbit, chicken, and shark do not. 2. Pepsin antisera react with both pepsin and pepsinogen, but do not react with the serum proteins from the homologous species. 3. Pepsinogen antisera react with pepsinogen, but not with twice crystallized pepsin, n...
متن کاملImmunochemical Studies on the Components of the Pepsinogen System
Rabbit antisera to pepsin and pepsinogen were characterized by several immunological criteria. Both antisera inhibited the rennet activity of pepsin. Antipepsinogen protected pepsin from alkaline denaturation. Using antipepsinogen, precipitin analysis at pH 5.5 indicated that the native enzyme resembles the precursor more closely than did the denatured enzyme. However, all three proteins have s...
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Phenylbutazone in moderate dosage has been administered to 15 patients with a variety of musculo-skeletal disorders. A rise in plasma pepsinogen activity occurred in 13, generally reaching a peak in the first week of treatment; subsequently there was a fall in spite of maintaining a constant dosage. In four of six patients an anticholinergic drug failed to prevent a rise in plasma pepsinogen ac...
متن کاملGastric Secretory Studies
This study compares the gastroprotective effects of colloidal bismuth subcitrate (DeNol) with those of sucralfate and a methylated analogue of prostaglandin E2 (PGE2) against acute gastric lesions induced by acidified aspirin and absolute ethanol in rats. Both De-Nol and sucralfate given orally prevented dose dependently the formation of gastric lesions by these ulcerogens, DeNol being, respect...
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ژورنال
عنوان ژورنال: Nihon Naika Gakkai Zasshi
سال: 1959
ISSN: 0021-5384,1883-2083
DOI: 10.2169/naika.48.390